Insulin translates unfavourable lifestyle into obesity


Lifestyle factors conferring increased diabetes risk are associated with elevated basal insulin levels (hyperinsulinaemia). The latter predicts later obesity in children and adolescents. https://bmcmedicine.biomedcentral.com/track/pdf/10.1186/s12916-018-1225-1

Autoren: Hubert Kolb, Michael Stumvoll, Werner Kramer, Kerstin Kempf and Stephan Martin


Lifestyle interventions have shown to be effective when continuous personal support was provided. However, there is lack of knowledge whether a telemedical-approach with personal coaching contributes to long-term weight losses in overweight employees. We, therefore, tested the hypothesis that telemedical-based lifestyle interventions accompanied with telemedical coaching lead to larger weight losses in overweight persons in […]

Autoren: Kerstin Kempf, Martin Röhling, Monika Stichert, Gabriele Fischer, Elke Boschem, Jürgen Könner and Stephan Martin


Formula diets can improve glycemic control or can even induce remission in type 2 diabetes. We hypothesized that especially an individualized intense meal replacement by a low-carbohydrate formula diet with accompanied self-monitoring of blood glucose (SMBG) contributes to long-term improvements in HbA1c, weight, and cardiometabolic risk factors in poorly controlled type 2 diabetes. https://www.mdpi.com/2072-6643/10/8/1022

Autoren: Kerstin Kempf, Martin Röhling, Katja Niedermeier, Babette Gärtner and Stephan Martin


Lifestyle interventions are the foundation of treatment in newly diagnosed type 2 diabetes. However, their therapeutic potential in advanced disease stages is unknown. We evaluated the efficacy of the Telemedical Lifestyle intervention Program (TeLiPro) in improving metabolic control in advanced-stage type 2 diabetes. http://care.diabetesjournals.org/content/diacare/40/7/863.full.pdf

Autoren: Kerstin Kempf, Bernd Altpeter, Janine Berger, Oliver Reuß, Matthias Fuchs, Michael Schneider, Babette Gartner, Katja Niedermeier and Stephan Martin


Lifestyle intervention in type 2 diabetes mellitus (T2DM) is effective but needs a special local setting and is costly. Therefore, in a randomized-controlled trial we tested the hypothesis that the autonomous use of the interactive exercise game Wii Fit Plus over a period of 12 weeks improves metabolic control, with HbA1c reduction as the primary […]

Autoren: Kerstin Kempf and Stephan Martin


Despite high insulin doses, good glycaemic control is often lacking in type 2 diabetes patients and new therapeutic options are needed. https://onlinelibrary.wiley.com/doi/abs/10.1111/jhn.12145

Autoren: K. Kempf, N. C. Schloot, B. Gärtner, R. Keil, P. Schadewaldt , S. Martin


The BI Employee study is a working population cohort. Employees (inclusion criteria: ≥38 years; employed for at least 2 years; no exclusion criteria) of BI Pharma GmbH & Co. KG were invited by the medical corporate department to participate in the prevention and health care programme “FIT IM LEBEN-FIT IM JOB”. This program is still […]

Autoren: Kerstin Kempf, Stephan Martin, Carmen Döhring, Klaus Dugi, Carolin Wolfram von Wolmar, Burkhard Haastert, and Michael Schneider